Evolutionary pattern of the H 3 haemagglutinin of equine influenza viruses: multiple evolutionary lineages and frozen replication
Identifieur interne : 001F76 ( Main/Exploration ); précédent : 001F75; suivant : 001F77Evolutionary pattern of the H 3 haemagglutinin of equine influenza viruses: multiple evolutionary lineages and frozen replication
Auteurs : A. Endo [Japon] ; R. Pecoraro [Japon] ; S. Sugita [Japon] ; K. Nerome [Japon]Source :
- Archives of Virology [ 0304-8608 ] ; 1992-03-01.
English descriptors
- Teeft :
- Amino, Amino acid sequence homologies, Amino acid sequences, Amino acid substitutions, Antigenic, Antigenic drift, Antigenic sites, Arch virol, Biol evol, Branch length, Certain period, Cocirculating lineages, Codon positions, Complete structure, Distinct lineages, Endo, Equine, Equine influenza, Equine influenza outbreak, Equine influenza virus, Equine influenza viruses, Equine virus, Equine viruses, Evolutionary, Evolutionary pathways, Evolutionary pattern, Evolutionary patterns, Evolutionary rate, Evolutionary relationships, Evolutionary tree, First stream, Gene, Haemagglutinin, Haemagglutinin gene, Haemagglutinin genes, Homology, Horse populations, Human influenza, Influenza, Influenza virus, Influenza viruses, Kawaoka, Large number, Lineage, Maximum parsimony method, Minor branches, Molecular evolution, Multiple lineages, National institute, Nonsynonymous, Nonsynonymous substitutions, Nucleotide, Nucleotide changes, Nucleotide sequences, Nucleotide substitutions, Oldest strain, Open circles, Outbreak, Pairwise comparison, Pathway, Phylogenetic, Phylogenetic analysis, Phylogenetic model tree, Phylogenetic tree, Present study, Previous reports, Putative root, Regression lines, Second codon positions, Second stream, Single lineage, Substitution, Synonymous substitution, Synonymous substitutions, Third codon position, Virol, Virological surveillance, Virology, Virus, Virus isolation, Virus isolations.
Abstract
Summary: The nucleotide and deduced amino acid sequences of the haemagglutinin genes coding for the HA 1 domain of H3N8 equine influenza viruses isolated over wide regions of the world were analyzed in detail to determine their evolutionary relationships. We have constructed a phylogenetic model tree by the neighbour-joining method using nucleotide sequences of 15 haemagglutinin genes, including those of five viruses determined in the present study. This gene tree revealed the existence of two major evolutionary pathways during a twenty five-year period between 1963 to 1988, and each pathway appeared to consist of two distinct lineages of haemagglutinin genes. Furthermore, our analysis of nucleotide sequences showed that two distinct lineages of equine H3N8 viruses were involved in an equine influenza outbreak during the period of December 1971–January 1972 in Japan. The number of nucleotide changes between strains was proportional to the length of time (in years) between their isolation except for three of the HA genes. However, there are three exceptional strains isolated in 1971, 1987, and 1988, respectively. The haemagglutinin gene in these strains showed a small number of nucleotide substitutions after they branched off around 1963, suggesting an example of frozen replication. Although the estimated rate (0.0094/site/year) of synonymous (silent) substitutions of the haemagglutinin gene of equine H3N8 viruses was nearly the same as that of human H 1 and H 3 haemagglutinin genes, the rate of nonsynonymous (amino-acid changing) substitutions of the former equine virus gene was estimated to be 0.00041/site/year — that is about 5 times lower than that estimated for the human H 3 haemagglutinin gene. The present study is the first demonstration that multiple evolutionary lineages of equine H3N8 influenza virus circulated since 1963.
Url:
DOI: 10.1007/BF01317139
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001491
- to stream Istex, to step Curation: 001491
- to stream Istex, to step Checkpoint: 000D27
- to stream Main, to step Merge: 002072
- to stream Main, to step Curation: 001F76
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evolutionary pattern of the H 3 haemagglutinin of equine influenza viruses: multiple evolutionary lineages and frozen replication</title><author><name sortKey="Endo, A" sort="Endo, A" uniqKey="Endo A" first="A." last="Endo">A. Endo</name></author><author><name sortKey="Pecoraro, R" sort="Pecoraro, R" uniqKey="Pecoraro R" first="R." last="Pecoraro">R. Pecoraro</name></author><author><name sortKey="Sugita, S" sort="Sugita, S" uniqKey="Sugita S" first="S." last="Sugita">S. Sugita</name></author><author><name sortKey="Nerome, K" sort="Nerome, K" uniqKey="Nerome K" first="K." last="Nerome">K. Nerome</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:B60F387437D65458C13EF23426C22EE1A2D46F0E</idno><date when="1992" year="1992">1992</date><idno type="doi">10.1007/BF01317139</idno><idno type="url">https://api.istex.fr/ark:/67375/1BB-4K2W686B-0/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001491</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001491</idno><idno type="wicri:Area/Istex/Curation">001491</idno><idno type="wicri:Area/Istex/Checkpoint">000D27</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000D27</idno><idno type="wicri:doubleKey">0304-8608:1992:Endo A:evolutionary:pattern:of</idno><idno type="wicri:Area/Main/Merge">002072</idno><idno type="wicri:Area/Main/Curation">001F76</idno><idno type="wicri:Area/Main/Exploration">001F76</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Evolutionary pattern of the H 3 haemagglutinin of equine influenza viruses: multiple evolutionary lineages and frozen replication</title><author><name sortKey="Endo, A" sort="Endo, A" uniqKey="Endo A" first="A." last="Endo">A. Endo</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Virology and Rickettsiology, National Institute of Health, Shinagawa-ku, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Pecoraro, R" sort="Pecoraro, R" uniqKey="Pecoraro R" first="R." last="Pecoraro">R. Pecoraro</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Virology and Rickettsiology, National Institute of Health, Shinagawa-ku, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Sugita, S" sort="Sugita, S" uniqKey="Sugita S" first="S." last="Sugita">S. Sugita</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Virology and Rickettsiology, National Institute of Health, Shinagawa-ku, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Nerome, K" sort="Nerome, K" uniqKey="Nerome K" first="K." last="Nerome">K. Nerome</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Virology and Rickettsiology, National Institute of Health, Shinagawa-ku, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Archives of Virology</title><title level="j" type="abbrev">Archives of Virology</title><idno type="ISSN">0304-8608</idno><idno type="eISSN">1432-8798</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Vienna</pubPlace><date type="published" when="1992-03-01">1992-03-01</date><biblScope unit="volume">123</biblScope><biblScope unit="issue">1-2</biblScope><biblScope unit="page" from="73">73</biblScope><biblScope unit="page" to="87">87</biblScope></imprint><idno type="ISSN">0304-8608</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0304-8608</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Amino</term><term>Amino acid sequence homologies</term><term>Amino acid sequences</term><term>Amino acid substitutions</term><term>Antigenic</term><term>Antigenic drift</term><term>Antigenic sites</term><term>Arch virol</term><term>Biol evol</term><term>Branch length</term><term>Certain period</term><term>Cocirculating lineages</term><term>Codon positions</term><term>Complete structure</term><term>Distinct lineages</term><term>Endo</term><term>Equine</term><term>Equine influenza</term><term>Equine influenza outbreak</term><term>Equine influenza virus</term><term>Equine influenza viruses</term><term>Equine virus</term><term>Equine viruses</term><term>Evolutionary</term><term>Evolutionary pathways</term><term>Evolutionary pattern</term><term>Evolutionary patterns</term><term>Evolutionary rate</term><term>Evolutionary relationships</term><term>Evolutionary tree</term><term>First stream</term><term>Gene</term><term>Haemagglutinin</term><term>Haemagglutinin gene</term><term>Haemagglutinin genes</term><term>Homology</term><term>Horse populations</term><term>Human influenza</term><term>Influenza</term><term>Influenza virus</term><term>Influenza viruses</term><term>Kawaoka</term><term>Large number</term><term>Lineage</term><term>Maximum parsimony method</term><term>Minor branches</term><term>Molecular evolution</term><term>Multiple lineages</term><term>National institute</term><term>Nonsynonymous</term><term>Nonsynonymous substitutions</term><term>Nucleotide</term><term>Nucleotide changes</term><term>Nucleotide sequences</term><term>Nucleotide substitutions</term><term>Oldest strain</term><term>Open circles</term><term>Outbreak</term><term>Pairwise comparison</term><term>Pathway</term><term>Phylogenetic</term><term>Phylogenetic analysis</term><term>Phylogenetic model tree</term><term>Phylogenetic tree</term><term>Present study</term><term>Previous reports</term><term>Putative root</term><term>Regression lines</term><term>Second codon positions</term><term>Second stream</term><term>Single lineage</term><term>Substitution</term><term>Synonymous substitution</term><term>Synonymous substitutions</term><term>Third codon position</term><term>Virol</term><term>Virological surveillance</term><term>Virology</term><term>Virus</term><term>Virus isolation</term><term>Virus isolations</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: The nucleotide and deduced amino acid sequences of the haemagglutinin genes coding for the HA 1 domain of H3N8 equine influenza viruses isolated over wide regions of the world were analyzed in detail to determine their evolutionary relationships. We have constructed a phylogenetic model tree by the neighbour-joining method using nucleotide sequences of 15 haemagglutinin genes, including those of five viruses determined in the present study. This gene tree revealed the existence of two major evolutionary pathways during a twenty five-year period between 1963 to 1988, and each pathway appeared to consist of two distinct lineages of haemagglutinin genes. Furthermore, our analysis of nucleotide sequences showed that two distinct lineages of equine H3N8 viruses were involved in an equine influenza outbreak during the period of December 1971–January 1972 in Japan. The number of nucleotide changes between strains was proportional to the length of time (in years) between their isolation except for three of the HA genes. However, there are three exceptional strains isolated in 1971, 1987, and 1988, respectively. The haemagglutinin gene in these strains showed a small number of nucleotide substitutions after they branched off around 1963, suggesting an example of frozen replication. Although the estimated rate (0.0094/site/year) of synonymous (silent) substitutions of the haemagglutinin gene of equine H3N8 viruses was nearly the same as that of human H 1 and H 3 haemagglutinin genes, the rate of nonsynonymous (amino-acid changing) substitutions of the former equine virus gene was estimated to be 0.00041/site/year — that is about 5 times lower than that estimated for the human H 3 haemagglutinin gene. The present study is the first demonstration that multiple evolutionary lineages of equine H3N8 influenza virus circulated since 1963.</div></front></TEI><affiliations><list><country><li>Japon</li></country><region><li>Région de Kantō</li></region><settlement><li>Tokyo</li></settlement></list><tree><country name="Japon"><region name="Région de Kantō"><name sortKey="Endo, A" sort="Endo, A" uniqKey="Endo A" first="A." last="Endo">A. Endo</name></region><name sortKey="Nerome, K" sort="Nerome, K" uniqKey="Nerome K" first="K." last="Nerome">K. Nerome</name><name sortKey="Pecoraro, R" sort="Pecoraro, R" uniqKey="Pecoraro R" first="R." last="Pecoraro">R. Pecoraro</name><name sortKey="Sugita, S" sort="Sugita, S" uniqKey="Sugita S" first="S." last="Sugita">S. Sugita</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F76 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001F76 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:B60F387437D65458C13EF23426C22EE1A2D46F0E
|texte= Evolutionary pattern of the H 3 haemagglutinin of equine influenza viruses: multiple evolutionary lineages and frozen replication
}}
| This area was generated with Dilib version V0.6.33. |  |